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+ Hormone replacement · Men & women

Your labs, read properly.

Testosterone and hormone therapy for men and women, including EvexiPEL pellets placed in-house. A full set of labwork first — always.

Shawn O’Keefe, PA-C, on hormone replacement at Twenty-One Medical and the practice’s partnership with Evexias Health Solutions. Captions are on screen throughout.

If you feel wrong and your labs were “normal,” read this.

Flat energy. Sleep that does not restore anything. Losing strength, gaining weight around the middle, a libido that quietly disappeared, a mood that is not yours. These are not character flaws and they are not simply age.

They are also not diagnosed by a questionnaire. Hormone replacement at Twenty-One Medical starts with a full set of labwork, an exam, and a conversation about what you are actually experiencing.

Hormone therapy for men

Testosterone replacement for men with confirmed low levels — diagnosed on bloodwork, dosed to your numbers and your symptoms, and monitored on an ongoing basis rather than set once and forgotten.

  • Full hormone and metabolic panel before anything is prescribed
  • Ongoing monitoring, because testosterone therapy changes more than testosterone
  • Dose adjusted to how you feel, not just what the labs say

Hormone therapy for women

Perimenopause and menopause management, plus treatment for women whose hormone symptoms started well before either. The same rule applies: labwork first, then a plan.

EvexiPEL pellet therapy

We place EvexiPEL hormone pellets in-house. A pellet is inserted under the skin in a short office procedure and releases hormone steadily over a period of months — no daily gel, no weekly injection to remember.

Pellets are not the right delivery method for everyone. Whether they fit depends on your labs, your symptoms and your preference, which is what the consult is for.

How scheduling works: request your initial consultation online. Hormone procedures, including pellet insertions, are scheduled by the office afterwards so the right time and supplies are set aside for you.

What to expect

STEP 01

Consult

Symptoms, history and goals, with a provider who has time for the whole list.

STEP 02

Full set of labwork

Hormones, thyroid and metabolic markers — not a single number in isolation.

STEP 03

Lab review

A dedicated visit to go through the results and decide together what to do about them.

STEP 04

Treatment & monitoring

Therapy started, then repeat labs and adjustments as your levels settle.

Common questions

My labs came back normal somewhere else. Why would it be different here?

“Normal” is a reference range covering a very wide population, and a single testosterone or TSH value does not describe a hormone system. We run a fuller set of labwork and read it against your symptoms rather than against the bottom edge of a range.

How long before I feel different?

It varies by person and by therapy. Most people notice changes over weeks rather than days, which is why the follow-up labs matter as much as the first prescription.

Is pellet therapy permanent?

No. Pellets release over a period of months and are re-placed on a schedule. If it is not working for you, you stop.

Do you treat both men and women?

Yes. Both are treated here, and both start the same way — with a consult, lab work and an individualized plan.

Is hormone therapy covered by insurance?

It depends on the plan and the therapy. Pellet procedures in particular are often not covered. Call the office and we will check yours before you book.

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Other care under the same roof.

Book with the provider you'll actually see.

Request a visit online, or call the office and talk to a person.